Search results for "model [particle]"

showing 10 items of 1261 documents

Microenvironment modulation and enhancement of antilymphoma therapy by the heparanase inhibitor roneparstat

2018

0301 basic medicinemedicine.medical_specialtyCancer ResearchLymphomaMice03 medical and health sciences0302 clinical medicineHematology; Oncology; Cancer ResearchInternal medicineTumor MicroenvironmentmedicineAnimalsHumansHeparanase030212 general & internal medicineEnzyme InhibitorsGlucuronidaseHematologyChemistryGeneral MedicineHematologyXenograft Model Antitumor AssaysNeoplasm Proteins030104 developmental biologyOncologyCancer research
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Metabolic syndrome enhances endoplasmic reticulum, oxidative stress and leukocyte–endothelium interactions in PCOS

2017

Polycystic ovary syndrome (PCOS) is associated with insulin resistance, which can lead to metabolic syndrome (MetS). Oxidative stress and leukocyte-endothelium interactions are related to PCOS. Our aim was to evaluate whether the presence of MetS in PCOS patients can influence endoplasmic reticulum (ER) and oxidative stress and leukocyte-endothelium interactions.This was a prospective controlled study conducted in an academic medical center. The study population consisted of 148 PCOS women (116 without/32 with MetS) and 112 control subjects (87 without / 25 with MetS). Metabolic parameters, reactive oxygen species (ROS) production, ER stress markers (GRP78, sXBP1, ATF6), leukocyte-endotheli…

0301 basic medicinemedicine.medical_specialtyXBP1Endocrinology Diabetes and Metabolism030209 endocrinology & metabolismBiologymedicine.disease_cause03 medical and health sciences0302 clinical medicineEndocrinologyInsulin resistanceInternal medicineCell AdhesionLeukocytesmedicineHumansProspective StudiesEndoplasmic Reticulum Chaperone BiPMetabolic SyndromeInterleukin-6ATF6Endoplasmic Reticulum StressIntercellular Adhesion Molecule-1medicine.diseasePolycystic ovaryOxidative Stress030104 developmental biologyEndocrinologyUnfolded protein responseHomeostatic model assessmentCytokinesFemaleEndothelium VascularMetabolic syndromeReactive Oxygen SpeciesCell Adhesion MoleculesOxidative stressPolycystic Ovary SyndromeMetabolism
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Does sex hormone-binding globulin cause insulin resistance during pubertal growth?

2019

Background The directional influences between serum sex hormone-binding globulin (SHBG), adiposity and insulin resistance during pubertal growth remain unclear. The aim of this study was to investigate bidirectional associations between SHBG and insulin resistance (HOMA-IR) and adiposity from childhood to early adulthood. Methods Participants were 396 healthy girls measured at baseline (age 11.2 years) and at 1, 2, 4 and 7.5 years. Serum concentrations of estradiol, testosterone and SHBG were determined by ELISA, glucose and insulin by enzymatic photometry, insulin-like growth factor 1 (IGF-1) by time-resolved fluoroimmunoassays, whole-body fat mass by dual-energy X-ray absorptiometry and …

0301 basic medicinemedicine.medical_specialtypubertyGlobulinEndocrinology Diabetes and Metabolismmedicine.medical_treatment030209 endocrinology & metabolismlcsh:Diseases of the endocrine glands. Clinical endocrinology03 medical and health sciences0302 clinical medicineEndocrinologyInsulin resistanceSex hormone-binding globulinInternal medicineinsulin resistanceInternal Medicinemedicinesex hormone-binding globulinkehonkoostumussukupuolihormonitadipositylcsh:RC648-665biologybusiness.industryResearchInsulinmenarcheConfoundinginsuliiniresistenssimurrosikämedicine.diseasetytöt030104 developmental biologyEndocrinologyglobuliinitHomeostatic model assessmentMenarchebiology.proteinbusinesshormones hormone substitutes and hormone antagonistsEarly pubertyEndocrine Connections
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An Efficient Cooperative Smearing Technique for Degraded Historical Documents Images Segmentation

2020

Segmentation is one of the critical steps in historical document image analysis systems that determines the quality of the search, understanding, recognition and interpretation processes. It allows isolating the objects to be considered and separating the regions of interest (paragraphs, lines, words and characters) from other entities (figures, graphs, tables, etc.). This stage follows the thresholding, which aims to improve the quality of the document and to extract its background from its foreground, also for detecting and correcting the skew that leads to redress the document. Here, a hybrid method is proposed in order to locate words and characters in both handwritten and printed docu…

050101 languages & linguisticsComputer sciencemedia_common.quotation_subject02 engineering and technologyImage (mathematics)Interpretation (model theory)[INFO.INFO-AI]Computer Science [cs]/Artificial Intelligence [cs.AI]0202 electrical engineering electronic engineering information engineering0501 psychology and cognitive sciencesSegmentationQuality (business)ComputingMilieux_MISCELLANEOUSmedia_commonbusiness.industrySmearing technique05 social sciencesPattern recognitionImage segmentationHybrid approachComputer Graphics and Computer-Aided DesignComputer Science Applications020201 artificial intelligence & image processingComputer Vision and Pattern RecognitionArtificial intelligencebusinessHistorical document
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Generating incremental type services

2019

In this vision paper, we propose a method for generating fully functional incremental type services from declarations of type rules. Our general strategy is to translate type rules into Datalog, for which efficient incremental solvers are already available. However, many aspects of type rules don't naturally translate to Datalog and need non-trivial translation. We demonstrate that such translation may be feasible by outlining the translation rules needed for a language with typing contexts (name binding) and bidirectional type rules (local type inference). We envision that even rich type systems of DSLs can be incrementalized by translation to Datalog in the future.

050101 languages & linguisticsLocal typeProgramming languageComputer science05 social sciencesName bindingInference02 engineering and technologyType (model theory)Translation (geometry)computer.software_genreDatalog0202 electrical engineering electronic engineering information engineering020201 artificial intelligence & image processing0501 psychology and cognitive sciencescomputercomputer.programming_languageProceedings of the 12th ACM SIGPLAN International Conference on Software Language Engineering
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A continuous time tug-of-war game for parabolic $p(x,t)$-Laplace type equations

2019

We formulate a stochastic differential game in continuous time that represents the unique viscosity solution to a terminal value problem for a parabolic partial differential equation involving the normalized $p(x,t)$-Laplace operator. Our game is formulated in a way that covers the full range $1<p(x,t)<\infty$. Furthermore, we prove the uniqueness of viscosity solutions to our equation in the whole space under suitable assumptions.

050208 financeLaplace transformApplied MathematicsGeneral MathematicsTug of warProbability (math.PR)010102 general mathematics05 social sciencesMathematical analysisType (model theory)01 natural sciencesParabolic partial differential equationTerminal valueMathematics - Analysis of PDEs0502 economics and businessDifferential gameFOS: Mathematics91A15 49L25 35K650101 mathematicsViscosity solutionMathematics - ProbabilityAnalysis of PDEs (math.AP)Mathematics
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‘Tool port’ to ‘landlord port’: a game theory approach to analyse gains from governance model transformation

2018

This study investigates potential port users’ surplus and terminal operators’ profits due to transforming port governance from the ‘tool port’ model to the ‘landlord port’ model. Although the landl...

050210 logistics & transportation021103 operations researchModel transformationCorporate governance05 social sciencesGeography Planning and Development0211 other engineering and technologiesOcean EngineeringTransportation02 engineering and technologyManagement Monitoring Policy and LawPort (computer networking)Terminal (electronics)0502 economics and businessBertrand competitionLandlordBusinesscomputerGame theoryIndustrial organizationcomputer.programming_languageMaritime Policy &amp; Management
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Competition for long-haul connecting traffic among airports in Europe and the Middle East

2017

Abstract This paper analyzes the competitive position of major hub airports in Europe and the Middle East for long-haul connecting traffic. We apply a connection builder to construct competitive flight connections. A stand out feature of the proposed connection builder is the calibration of the model parameters using booking data, composed of actual passenger demand between a given origin and destination (O&D) market. The methodology is applied to measure competition between hubs using flight schedule data to calculate connectivity measures like the number of city-pairs connected via a hub airport. Our results show that the Middle Eastern hubs have improved their competitive position, while…

050210 logistics & transportationMiddle EastOperations researchbusiness.industry020209 energyStrategy and Management05 social sciencesTransportationModel parametersComputer Science::Social and Information Networks02 engineering and technologyManagement Monitoring Policy and LawCompetition (economics)Network management0502 economics and businessFlight schedule0202 electrical engineering electronic engineering information engineeringPosition (finance)businessTelecommunicationsLawJournal of Air Transport Management
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Progress Checking for Dummies

2018

Verification of progress properties is both conceptually and technically significantly more difficult than verification of safety and deadlock properties. In this study we focus on the conceptual side. We make a simple modification to a well-known model to demonstrate that it passes progress verification although the resulting model is intuitively badly incorrect. Then we point out that the error can be caught easily by adding a termination branch to the system. We compare the use of termination branches to the established method of addressing the same need, that is, weak fairness. Then we discuss another problem that may cause failure of catching progress errors even with weak fairness. Fi…

060201 languages & linguisticsModel checkingComputer scienceusability of verification methodsalgoritmiikkafairness06 humanities and the arts02 engineering and technologyfair testingDeadlocktestausverifiointiRisk analysis (engineering)edistys0602 languages and literature0202 electrical engineering electronic engineering information engineering020201 artificial intelligence & image processingPoint (geometry)ohjelmointiSet (psychology)Focus (optics)Simple (philosophy)
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On the Almost Everywhere Convergence of Multiple Fourier-Haar Series

2019

The paper deals with the question of convergence of multiple Fourier-Haar series with partial sums taken over homothetic copies of a given convex bounded set $$W\subset\mathbb{R}_+^n$$ containing the intersection of some neighborhood of the origin with $$\mathbb{R}_+^n$$ . It is proved that for this type sets W with symmetric structure it is guaranteed almost everywhere convergence of Fourier-Haar series of any function from the class L(ln+L)n−1.

40A05Control and OptimizationBounded set (topological vector space)Type (model theory)01 natural sciencesmultiple Fourier-Haar seriesHomothetic transformationCombinatoricssymbols.namesakeSettore MAT/05 - Analisi Matematica0103 physical sciences42C10Almost everywhere0101 mathematicsMathematicsSeries (mathematics)Applied Mathematics010102 general mathematicsRegular polygonAlmost everywhere convergenceFunction (mathematics)Fourier transformsymbols010307 mathematical physicslacunar serieAnalysisJournal of Contemporary Mathematical Analysis (Armenian Academy of Sciences)
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